NCAM as a cystogenesis marker gene of PKD2 overexpression
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چکیده
منابع مشابه
NCAM as a cystogenesis marker gene of PKD2 overexpression.
ADPKD (Autosomal Dominant Polycystic Kidney Disease) is characterized by the progressive expansion of multiple cystic lesions in the kidneys. ADPKD is caused by mutations in Ed-pl. consider PKD1 and PKD2. Recently a relation between c-myc and the pathogenesis of ADPKD was reported. In addition, c-Myc is a downstream effector of PKD1. To identify the gene regulated by PKD2 and c-Myc, we performe...
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ژورنال
عنوان ژورنال: BMB Reports
سال: 2008
ISSN: 1976-6696
DOI: 10.5483/bmbrep.2008.41.8.593